Apr 21, 2022 | Uncategorized
Getting old is a term that’s not high on popularity polls and has even been the subject of nightmares for many great men. Everyone wishes for their fountain of youth to never run dry. However, youth is a gift of nature that comes attached with its own stop clock. Which brings us to the all important question — Are you really as old as you think you are?
Perhaps not. When explaining age, scientists use two definitions — chronological age and biological age. Chronological age is the time passed from the time of your birth. Every birthday you celebrate marks the progression of your chronological age. However, individuals with the same chronological age vary widely in health and the kind of feats they achieve in their daily lives. For instance, someone who is 50 might have the dexterity of a 30-year-old. They could climb flights of stairs with ease or have no trouble with vision in low lights. This concept of functional age is what scientists call Biological age. It defines how your biological system is aging. So at a specific chronological age, one’s biological age can be younger or older.
Being functional in nature, biological age measures the aging process in terms of various components such as functional impairment, disease, and morbidity.
In recent times, scientists have identified “Biomarkers” that govern Biological age. These can be broadly categorized into Molecular biomarkers– based on genetic material like DNA, RNA etc or Phenotypic biomarkers based on clinical parameters like blood pressure, grip, muscle strength, lipids etc. Scientists have made remarkable breakthroughs in assessing the biological age through these markers.
One popular method of biological age quantification in the molecular biomarker category is the Epigenetics clock. Epigentics clock or DNA methylation age ( DNAmAge for short) is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. In an adult human being, the rate of methylation correlates with age for a specific site. Ainsi, inutile de vous déplacer en parapharmacie ou dans des magasins spécialisés asgg.fr/ ! This concept is used to create the epigenetic clock. Scientists have used the epigentic clock to determine tissue age, lung age etc. Another popular biological age quantification method is through telomeres. Telomeres are protective caps on your chromosome and are maximum at the time of birth. As cell division happens, based on the number of generations, the size of telomeres starts to reduce. The reduction in size correlates with age and has been linked with associated diseases like diabetes, alzheimers, hypertension etc. Thanks to the remarkable understanding scientists now have about aging, we also have many other approaches to determine biological age.
Unlike chronological age, biological age is something you can control and reverse. Today biologically you might be 45 and the very next year, you could very well be 5 years younger. This is possible because we now have greater understanding of cellular and molecular mechanisms that govern aging. The rate of senescence can be reversed or, atleast slowed through simple ways.
Aristotle once said, “you are what you eat”. Even after centuries this stands true. Diet plays an important role in your aging process. Just like fueling your vehicle with the wrong fuel can be detrimental to the engine, an unhealthy or wrong diet can expedite one’s aging process. Diet rich in antioxidants, beta carotenes, omega-3 and polyphenols are known to keep one’s body young.
Inclusion of 30 minutes of exercise each day is extremely important for your cellular regeneration and repair. Mild cardio exercises will also help one better adapt to aging. Apart from diet and lifestyle, stress plays a crucial role in aging related processes. Stress can damage your body and make you feel older than you really are. Pent-up emotions and anger need to be released in a healthy manner. Research shows activities like Yoga, meditation or even deep breathing goes a long way in keeping one young and energetic.
Sleep is another crucial aspect that decides how fast you age. sleep deterioration has been linked to such conditions as Alzheimer’s disease, heart disease, obesity, diabetes, and stroke. More than quantity it is the right quality of the sleep that helps you to stay young. Deep curative sleep not only slows down the aging of the brain but also promotes neurochemicals that help us switch stably from state of sleep to wakefulness.
When people say that age is just a number, they mean the chronological age. With proper diet and lifestyle adjustments, you can be of the age you want to be, and your birthday parties may no longer stand testament to your true age.
Apr 21, 2022 | Uncategorized
The Human Genome Project of the 1990s, was the largest collaborative project in the field of biology. Through this project, researchers shed light on the structure and function of entire DNA in the human genome, which enabled jump-start a whole new world of sciences, such as Nutrigenomics. A growing interest in preventive medicine among people led to scientific research on alternative therapies, with particular emphasis on nutritional approaches to health and wellness. Utilizing knowledge from various areas of study such as Nutrition, Bioinformatics, Molecular Biology and Genomics, Nutritional genomics or Nutrigenomics is an emerging field of study that unveils the complex interrelationship between genes, nutrition, health and disease. En plus des conseils délivrés par des pharmaciens, votre parapharmacie discount vous asgg.fr/ offre la possibilité de laisser des avis produits (modérés par nos professionnels diplômés en pharmacie) ou des avis sur la qualité de nos services afin d’être la plus transparente possible avec vous. This field of science focuses on the impact of food (nutrients), on our body as a system, by identifying its impact at the building block (genetic) level. Simply put, what we eat, directly determines the genetic messages that our body receives, and these genetic messages control all the molecules and nutrient pathways that are part of our metabolism. Nutrigenetics like Nutrigenomics is a closely related area of study on diet(nutrient) -gene interaction but focuses on the inverse relationship of how our genetic profiles determine our response to food(nutrients).
The human diet is a cocktail of nutritional and chemical molecules each capable of regulating various inter-connected molecular mechanisms in various tissues throughout the body. Thus, if we learn the language of our genes, and learn to control the messages they give our body (through personalization of nutrition), we can radically change the way we view food, not just as a means of sustenance, but as medicine -to stall the inevitable rigors of ageing and achieve optimal health.
Nutrigenomics and Nutrigenetics draws together cellular & molecular biology, biochemistry and genetics to paint a comprehensive picture of our body as an intricately connected physiological network. This integrated approach is a per-requisite to realize the ambitious goals of tailor-made nutrition.
Although Nutrition science has long been used for dietary recommendations to control risk of certain lifestyle conditions like coronary heart disease, Type 2 Diabetes, and Obesity to name a few, the precise mechanism through which these recommendations regulate health and disease have been slightly enigmatic. Reason being, we have always observed vastly different responses between individuals to a given diet or nutritional recommendation, and that is attributed to differences in their underlying genetic makeup. It is precisely this gap that Nutrigenomics can bridge, by giving us a better understanding of nutrient-gene interactions, to determine how much of a specific nutrient(or food factor) YOUR body dictates as its “standard”, thus enabling personalized nutritional recommendations.
For example, caffeine (consumed through various beverages like tea /coffee) — can cause an increased risk of heart disease for some individuals who are “slow” metabolizers of caffeine, whereas “fast” metabolizers actually see the opposite effect where caffeine may have protective benefits on their body.
The field of Nutrigenomics has been facilitated greatly by our recent entrance into the post-genomic era, which brought with it, the development of genetic research platforms like Proteomics, Metabolomics and Transcriptomics. Proteomics refers to the large-scale study of proteins produced and modified by an organism. Metabolomics refers to the large-scale study of small molecules known as metabolites and their interactions within the biological system. Transcriptomics refers to the study of complete set of RNA transcripts that are produced by the genome under specific circumstances. All these genetic research platforms use genetic and molecular tools such as micro-array analysis and complementary data mining algorithms, that enable us to comprehensively study, interpret and unravel the role of nutrients in the human biological system.
Though the genes we inherit cannot be altered, one can certainly change their response to the environment (dietary choices) and optimize health. Nutrigenomics research is a basis for identifying molecular biomarkers (nutrients and/or their combinations) that manipulate gene expression, for developing the concept of “personalized diets”. This is an extremely critical aspect in the early phase of diet related diseases; the phase at which, intervention with nutrition can return the person to health.
Integrating genetics into public health in India, requires an increase in general public awareness about how changes in lifestyle and dietary habits can contribute to a longer, healthier life. Past and present food scares, such as genetically modified crop & livestock demonstrate the undeniable importance of regulation, ethics and public awareness to ensure responsible use of Nutrigenomics research.
On one hand we have DNA, the epitome of biological science and the other, we have nutrition, the most potent, modifiable environmental factor in human life. As the scientific community gains further insight into interactions between genotype and lifestyle, we will be able to reshape nutrition science, and step closer to the highly desirable goal of personalized nutrition.
The ultimate aim of Nutrigenomics follows the dictate from Hippocrates ,the Father of Medicine — “Leave your drug in the chemist’s pot if you can heal the patient with food.”
Apr 19, 2022 | Uncategorized
Researchers have predicted that obesity might be another pandemic of the 21st century. According to a survey, 36% of adults are overweight, and it will continue to grow. We are well aware of it as well. Most of us have tried different diet plans, different exercise programs to achieve our new year fitness goal, yet the results are not very convincing.
The hardest part of following a nutritional diet plan is being consistent. People are finding it difficult to sustain a diet plan for so long. We understand your concern because sometimes, nutritional diet plans that our health coaches have prescribed are hard to follow. It might be very generic and simply not meant for your body type. There is no one diet fits all strategy.
A nutritional plan or diet must be specific to your body type and must be a sustainable diet that sticks long. In this article, we will discuss how nutrigenomic is a more sustainable way to achieve your fitness goals.
Most people go to their health coaches, nutritionists or dieticians for a nutritional plan to achieve specific goals in fitness. The problem with these generic nutritional plans is that they are very generic and based on trial and error.
Nutrigenomic plans are very different as they are very specific, not generic. It looks at multiple aspects like what is it that your DNA interacts best with and the deficiencies that you are either already facing or most prone to facing before creating a nutritional plan.
When we break down the word Nutrigenomic which is a fusion of two words, nutrient and genomic, Nutri means the nutrition or the nutritional aspect and Genomic means through the DNA. So, it is a plan that is created through your DNA. It is essentially the epitome of personalization, and you do not get a more personalized nutritional plan than nutrigenomic.
How does nutrigenomic specify a diet that works for you?
When we look into DNA, it talks about different factors like the interaction of other macros in your DNA. In weight loss, the first thing that people generally do is go into a calorie deficit diet. Calorie deficit or calorie restriction has created a buzz for a while. But only 28% of our population experience a positive result in calorie restriction, and 72% do not see any effect. It suggests that calorie deficit or calorie restriction is not the solution.
If we look through the eyes of nutrigenomic or through DNA, there is a logic behind the fact.
In the past, there was famine. People were deprived of food for a long time, and that information is stored in our DNA.
Our bodies are remarkably adaptive, and they adapt to calorie deficit very easily.
When we are in a calorie deficit, it reduces the BMR or Basal Metabolic Rate. It is the energy required by the body while resting, and low BMR decreases metabolic efficiency. So, our body adapts and sustains itself wonderfully in a calorie deficit diet.
But a calorie deficit diet cannot go on for a long time. Everybody hates being hungry for the rest of their life. Practically you will put your body under restriction for two to three months then you will be out of it. Once you move out of calorie restriction, your body will see a lot of calories flooding in. It will result in gaining back all the weight you have lost in the diet. It can also result in bloating and other health issues.
Understanding the interaction between macros and your body.
Let us take fats into account. We have analyzed that 36% of our population are susceptible to saturated fats, and these fats are in packaged foods like chips. If you are falling in this cohort of people that are sensitive toward saturated fat, then a calorie deficit diet would not be very beneficial for you. Cutting out saturated fat decreases your BMI by about 10%, and there is research evidence to showcase this across. Therefore, it is vital to understand how your body reacts with these aspects before deciding what works and does not work for you.
Nutrigenomic does not put you through a calorie deficit diet because it may give you short term results but may affect you negatively in the long term. It is not only about what you will achieve in the next two to three months, but it is about how your life will be for the next 30 years. That is important for Nutrigenomic and you as well. Our goal is to make your today healthier and ensure that your life is throbbing with energy when you hit your late 70’s. So, by the time you reach 70, where most of the health problems start occurring, your body is already resilient. Your old age will still be your prime time.
The benefit of Nutrigenomic diet over generic diet
There is a lot of evidence of a nutrigenomic diet. Following a Nutrigenomic plan is much easier than following a generic plan. There are two reasons behind the success of a nutrigenomic diet. First, a Nutrigenomic diet plan can look into various aspects of the body that a generic diet plan cannot look at.
Second, consuming food in line with your DNA impacts our body more quickly than a generic plan.
In some cases, people have experienced higher energy levels within 12 days of starting the plan. They said that they do not feel fatigued or tired anymore. So, it makes people stick to the diet plan as the result they want is quicker than expected.
Third, It knows how your food will interact with the body, and it delivers to its targeted parts with no adverse effects on the body.
So it becomes three times more easier to follow and five times when it comes to the result that it delivers.
These numbers come from Peer-reviewed journals, which have established research behind these numbers. Hence, Nutrigenomic is more confident that these plans will help you achieve the result you want more efficiently and sustainably. Tout employe viagra pour homme du genre vont reveler son secret: c’ est un comprime de pilules que n’ importe quel homme va faire un super- heros.
Conclusion
Apart from the fact that it works especially to achieve your fitness goals, it also has psychological aspects. You will feel motivated to follow the nutrigenomic plan, which is meant specifically for your body. Knowing that this is categorically designed to keep you as the centre of the universe helps you adorn the role and take action accordingly. It gives you the power in your hands to change what you want to change and the way you want to change. It is the most vital point when it comes to nutrition.
Take a step*(CTA directing to book page)* by adopting Nutrigenomic in your life, and we assure you to make your present and future healthier.
Apr 19, 2022 | Uncategorized
Superfood can be defined as the food that addresses most deficiencies in a single shot. There are no hard and fast rules that these sorts of food are superfoods, and it varies from person to person. Le resultat https://asgg.fr/ etait exceptionnel. Some foods can be very beneficial for specific people and general for some. DNA testing can help you identify your deficiencies and recommend specific foods to address them specifically. Hence, Personalized superfoods.
In this article, we will discuss How genetic testing helps identify what the superfoods for our system are.
DNA testing does not decide whether Mango/Jamun food is good for you or not. The DNA test enables us to identify the most common deficiencies with a high propensity.
In a standard blood checkup, you will understand vitamin D deficiency and vitamin D 12. But in DNA testing, you’re able to look at vitamin A and tire B complex C, vitamin D, vitamin K, calcium, magnesium, iron, zinc, and the entire gene bank. It will help to understand the micronutrients that have the highest chance of being deficient in your body and recommend the right kind of food that will take care of those deficiencies.
Personalize superfoods
Each person faces different deficiencies and a different set of health conditions. Each person’s body also reacts differently to micronutrients. So the superfood will also be different for each person.
For example, Kidney beans can be a superfood for some people and ordinary food for many people. But kidney beans can solve many deficiencies in a single shot. If a person is diagnosed with such deficiency, kidney beans might be a superfood for him.
So, In lifestyle analysis and recommendation, We give them 7 to 10 superfoods per person. Sometimes it is tough to accept a diet plan and lifestyle, but adding these 7–10 superfoods to your diet might be easy. This is the Idea behind personalized superfoods.
Soul foods
Some foods can be terrible for someone but might be super beneficial for others. These are are the superfoods as we discussed earlier in this article.
Apart from that, some food works brilliantly for our system. These foods come into the soul food category. In soul food, certain parts of fruits, veggies, grain, and oil are considered that respond well to your body. These plans help you achieve your goals and solve several deficiencies that you did not even know you were facing.
Our body has been a very robust entity for a very long time. It tries to negate any adverse effects that you are doing. But every living biological aspect has a threshold beyond which it breaks. Our entire effort is to try and put you behind that nodal point where this change actually occurs. We ensure the change occurs in a positive direction. Being consistent will yield the results you have wanted for a long time.
DNA testing for diet and fitness
Most of the conditions related to diet and fitness are known as polygenic conditions. It essentially means that it is not governed by one gene. Multiple genes interact together to result in a particular phenotype. This phenotype is what we see on the external body. Science is developing around this topic.
If the markers, we are aware of are higher in number, the better will be the result that we can provide across certain conditions. Only two different genes govern certain traits like Lactose intolerance as it is just a single enzyme, and with those two markers, it is possible to get well over 90% accuracy. But in diet and fitness, we have to know how our body interacts with carbs or proteins, and these conditions are highly polygenic traits.
In certain highly polygenic traits like diabetes, getting well over 80% accuracy is possible. But in certain parts like in fitness, accuracies will be lower. It can be as accurate as well over 90% in monogenic, but if there are three to seven markers, it can be as low as 80%. Research is still going on to address these areas. Once the science around this topic evolves, our predictions and recommendations will also keep growing.
How do these DNA tests work?
DNA creates proteins in the form of RNA, and then RNA leads the development of the proteins and does a lot of work inside the body. Then, regulatory elements within the DNA talk about when and what protein needs to be expressed.
There are 3 billion base pair long molecules called the DNA with variations at different places. Many of these variations have been accounted for in Human Genome Projects, and these areas are known as hotspots.
Mutation or polymorphism, as commonly called, are seen in these areas. We are different from each other at these points. Over 99.7% of our DNA is very similar to every person, and only 0.3% are different, which is the deciding factor in every human being. Hence, the hotspot. Nugenomic focuses on how your hotspots are different from everybody else and help people find out the health trajectory that they might be taking. It is a complete understanding of the past, used in the present, to optimize your future.
Apr 15, 2022 | Uncategorized
A lot of discussions are going around treating lifestyle disorders. Is it possible to treat lifestyle disorders, or do we have to deal with it throughout our lives?
In this article, we will help you understand more about lifestyle disorders and how lifestyle analysis can help in treating Lifestyle diseases like Diabetics, chronic gastric, and certain types of cancer.
When it comes to lifestyle analysis, let us understand it by taking a few data points. Most of the Indian population is on either side of the BMI chart. A large part of the population is overweight, whereas a minor part is malnourished or underweight.
Similarly, over 60% of our geriatric population suffers from gastric distress. It starts to incubate from a very early stage of our life due to food intolerance that we accumulate inside our bodies. Over 77 million people suffer from diabetics in India, which is the second most affected world after China. Our 10 million population is in hypertension. These are all well-known lifestyle diseases, along with certain types of cancer.
So, professional lifestyle analysis can help you detect all these lifestyle diseases and disorders beforehand. It can prevent a lot of chronic conditions and diseases that we face and ensure excellent health. It can help you live a better life without medications if we focus on food as medicine.
The father of medicine, Hippocrates, has also said that “Let food be thy medicine and medicine be the food.”
With lifestyle analysis, we can rectify a lot of these conditions. You can be a far different person just by eating healthy and doing what your body is meant to do.
Lifestyle analysis in preventing gastric condition and food intolerance
Looking at the stats of India, over 60% of our population is lactose intolerant, with 20% of us being intolerant towards gluten, which is wheat. It is the staple food of India.
Intolerance works very differently than allergies. Consuming food that you are allergic to elicits an allergic response immediately. However, food intolerance festers inside the body for years, causing slight gut inflammation with multiple effects. One of this slight inflammation is called a subclinical inflammation. It increases the oxidative stress on the body. Oxidative stress fastens your ageing process.
On top of that, inflammation hampers the absorption of nutrients from the food that you consume. It keeps on increasing over a while. When you reach 55 or 60, you will begin to have supplementary bowel syndrome and gut ulcers.
Food intolerance starts at a very initial stage and keeps on accumulating over time. We can detect food you are intolerant to beforehand, like if you have hypertension, you may be salt sensitive. With lifestyle analysis, we give you corrective recommendations so that these conditions do not come up in the future.
Importance of lifestyle analysis for fitness.
People try out different kinds of diets like Keto, Paleo, or the Mediterranean. These diets have a specific amount of carbohydrates, proteins, and fats.
But interestingly, not every diet works the same for all people. For example, Keto diets are high in proteins and fats, but they do not give every person the same results. A Keto diet might benefit some people, but some may get an adverse effect. The high protein diet may throw off the bilirubin levels all over the place and pull your uric acid level. With a high-fat diet, some may get problems like higher cholesterol level.
But with lifestyle analysis, we can see how these macronutrients interact with your body and what concentration of different macronutrients is best suited for you. On that basis, we recommend an ideal nutrition intake plan. It will help you to achieve your fitness goals like weight loss or weight gain very effectively. Identifying the exact proportion of macros for the body will also help people in rehab, optimize their health not only for today but for a very long time.
Problems with modern-day diet plans
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Today most of the people in India are either overweight or underweight. Most professional diets suggest a high protein diet to every problem as if it is the magic bullet for whatever fitness goals you want to achieve.
A general notion that is circulating in the fitness industry is to cut carbs and lose weight. But that is not true in every case. Some people have a body type that loses weight when given a high-carb diet. Amos Oz fut de son vivant l’ un https://asgg.fr/ des plus lus dans le monde. A high-carb diet does not mean cakes and pastries but a pure Mediterranean diet that includes fresh fruits and veggies. For some people, a diet like Keto and Atkin might work well.
Similarly, Some of the body types accept a high-fat diet as well. Their body uses fats as fuel more efficiently, which is also known as Beta-Oxidation. A high-fat diet is considered great for your mental health as it is the source for the brain.
In a lifestyle analysis, we consider your body type and how different nutrients will interact with your body. Depending on the goals you want to achieve, we prepare an ideal nutrition plan that best suits you.
Change in lifestyle patterns can help you achieve optimum health.
People can lose weight by changing their sleeping patterns, as the circadian rhythm is an essential aspect of RTC.
It is because, Over a million years of our evolution, we have gone through drought and flood where there was a deprivation of food. But for the first time in human history, most people are deprived of sleep.
There were light-outs, and people used to sleep in the past as there was nothing important to do in the dark. But now, the time is different, and people are consciously depriving themselves of quality sleep.
So, just correcting the sleeping patterns and giving your body the amount of sleep it requires at the right time can help you reduce a significant amount of weight. A lot of metabolic processes in our body fall into the right place. This increases your metabolic efficiency and BMR and leads you towards a healthy lifestyle.
How Nugenomics works towards better human health?
Nugenomics not only focuses on lifestyle analysis. We look into the absolute basic of your body which is your DNA.
There are millions of variations within the DNA for each one of us. These variations react differently to the environment they are present. Therefore, it creates a unique person that is you. We look at these variations to understand, what are the potential routes that you can be taking. We understand the blood biomarkers to know which one of those routes that you have already taken. On top of that, we do a lifestyle analysis to understand what triggered your gene in the manner that they say because of which you are. We understand why you end up where you are.
And with this complete information, we can provide actionable recommendations in terms of lifestyle and nutrition. This is the USP of Nugenomics. It will pull you back from the track you have already headed down and put you on a better, more sustainable track point.
How does Nugenomics help you to change your lifestyle pattern To achieve your health goals?
There are various aspects that we consider into this. For instance, let us take food patterns into account.
We identify your current patterns that are working well for you and to what food you are inclined. We consider those and give recommendations that come close to your current lifestyle as much as possible to stick to it easily and achieve the desired result.
Implementing these micro recommendations every day would significantly impact your health without much affecting your current lifestyle. Based on these micro results, we have been able to get results in controlling blood pressure and weight loss.
Conclusion
Consistency is the key. Some minor changes in the lifestyle can help you reverse your biological age if you maintain it for a long time. A little quote from the film “Dennis the Menace” will make perfect sense to this topic that is “A little progress every day adds up to big results.” These minor tweaks over a while will impact your health in a big way which you would have never imagined.
